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Easily clip, save and share what you find with family and friends. Easily download and save what you find. The low blood pressure can be severe. Nitroglycerin was written about as early as 1846 and came into medical use in 1878.
Three different forms of nitroglycerin: intravenous, sublingual spray, and the nitroglycerin patch. NO as the responsible agent was known. This led to the development of transdermal patches of glyceryl trinitrate, providing 24-hour release. 3 weeks of sustained use. Thus, glyceryl trinitrate works best when used only in short-term, pulse dosing. It may also be given as a sublingual or buccal dose in the form of a tablet placed under the tongue or a spray into the mouth for the treatment of an angina attack.